Divestiture • Life Science

TransCode Acquires Polynoma

On October 8, 2025, TransCode acquired life science company Polynoma from CK Life Sciences Int’l.

Acquisition Context
  • This is TransCode’s 1st transaction in the Life Science sector.
  • This is TransCode’s 1st transaction in the United States.
  • This is TransCode’s 1st transaction in California.

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M&A Deal Summary

Date October 8, 2025
Target Polynoma
Sector Life Science
Buyer(s) TransCode
Sellers(s) CK Life Sciences Int’l.
Deal Type Divestiture

Target Company

Polynoma

San Diego, California, United States
Polynoma is a U.S. immuno-oncology-focused biopharmaceutical company using its lead asset, a novel polyvalent shed antigen vaccine, seviprotimut-L, for the prevention of recurrence of melanoma. Polynoma is based in San Diego, California.
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Buyer Overview 1

Buyer

TransCode

Newton, Massachusetts, United States

Category Company
Sector Life Science
DESCRIPTION

TransCode is a clinical-stage oncology company focused on treating metastatic disease. The Company is committed to defeating cancer through the intelligent design and effective delivery of RNA therapeutics based on its proprietary TTX nanoparticle platform. TransCode lead therapeutic candidate, TTX-MC138, is focused on treating metastatic tumors that overexpress microRNA-10b, a unique, well-documented biomarker of metastasis. In addition, it has a portfolio of other first-in-class RNA therapeutic candidates designed to overcome the challenges of RNA delivery and thus unlock therapeutic access to a variety of novel genetic targets that could be relevant to treating a variety of cancers. TransCode is based in Newton, Massachusetts.


Deal Context for Buyer #
Overall 1 of 1
Sector: Life Science 1 of 1
Type: Divestiture 1 of 1
State: California 1 of 1
Country: United States 1 of 1
Year: 2025 1 of 1

Seller Profile 1

SELLER

CK Life Sciences Int’l.

Tai Po, China

Category Company
Founded 1999
Sector Life Science
Employees1,935
Revenue 5.5B HKD (2024)
DESCRIPTION

CK Life Sciences Int’l. is an entity that bears the mission of improving the quality of life, CK Life Sciences is engaged in the business of research and development, commercialisation, marketing and sale of health and agriculture-related products. CK Life Sciences Int’l was founded in 1999 and is based in Tai Po, China.


Deal Context for Seller #
Overall 1 of 1
Sector: Life Science 1 of 1
Type: Divestiture 1 of 1
State: California 1 of 1
Country: United States 1 of 1
Year: 2025 1 of 1
PREVIOUS DEAL
DATE TARGET DEAL TYPE VALUE
2025-10-08 TransCode

Newton, Massachusetts, United States

TransCode is a clinical-stage oncology company focused on treating metastatic disease. The Company is committed to defeating cancer through the intelligent design and effective delivery of RNA therapeutics based on its proprietary TTX nanoparticle platform. TransCode lead therapeutic candidate, TTX-MC138, is focused on treating metastatic tumors that overexpress microRNA-10b, a unique, well-documented biomarker of metastasis. In addition, it has a portfolio of other first-in-class RNA therapeutic candidates designed to overcome the challenges of RNA delivery and thus unlock therapeutic access to a variety of novel genetic targets that could be relevant to treating a variety of cancers. TransCode is based in Newton, Massachusetts.

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