M&A Deal Summary

Tempest Therapeutics Acquires Factor Bioscience - Dual-CAR T Programs

On November 19, 2025, Tempest Therapeutics acquired life science company Factor Bioscience - Dual-CAR T Programs from Factor Bioscience

Acquisition Highlights
  • This is Tempest Therapeutics’ 2nd transaction in the Life Science sector.
  • This is Tempest Therapeutics’ 2nd transaction in the United States.
  • This is Tempest Therapeutics’ 1st transaction in Massachusetts.

M&A Deal Summary

Date 2025-11-19
Target Factor Bioscience - Dual-CAR T Programs
Sector Life Science
Buyer(s) Tempest Therapeutics
Sellers(s) Factor Bioscience
Deal Type Divestiture

Target

Factor Bioscience - Dual-CAR T Programs

Cambridge, Massachusetts, United States
Factor Bioscience's Dual-CAR T Programs are specifically designed to target patients with extramedullary disease (EMD), which we are referring to as TPST-2003 and are based in Cambridge, Massachusetts.

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Buyer(S) 1

Buyer

Tempest Therapeutics

Brisbane, California, United States

Category Company
Founded 2011
Sector Life Science
Employees24
Revenue 29M USD (2023)
DESCRIPTION

Tempest Therapeutics is a clinical-stage oncology company advancing small molecules that combine both targeted and immune-mediated mechanisms with the potential to treat a wide range of tumors. Tempest Therapeutics is developing an inhibitor of TREX-1, a double-stranded DNA exonuclease that is designed to control activation of the cGAS/STING pathway, which is an innate immune response pathway that induces the production of IFN-?, a cytokine that is well-established to trigger the development of anti-tumor immunity. Tempest Therapeutic is based in Brisbane, California.


DEAL STATS #
Overall 2 of 2
Sector: Life Science M&A 2 of 2
Type: Divestiture M&A Deals 1 of 1
State: Massachusetts M&A 1 of 1
Country: United States M&A 2 of 2
Year: 2025 M&A 1 of 1
PREVIOUS DEAL
DATE TARGET DEAL TYPE VALUE
2021-03-29 Millendo Therapeutics

Ann Arbor, Michigan, United States

Millendo Therapeutics is focused on developing novel treatments for endocrine diseases. Millendo Therapeutics creates distinct and transformative treatments for a wide range of diseases where there is a significant unmet medical need. Millendo Therapeutics is based in Ann Arbor, Michigan.

Buy -

Seller(S) 1

SELLER

Factor Bioscience

Cambridge, Massachusetts, United States

Category Company
Founded 2011
Sector Life Science
DESCRIPTION

Factor Bioscience develops technologies for engineering cells to advance the study and treatment of disease. Factor Bioscience developed the fastest, highest-efficiency method for reprogramming somatic cells to a pluripotent stem-cell state, a key invention now recognized by several patents. This technology, which enables the production of patient-specific cells for transplantation, has wide-ranging applications in personalized regenerative medicine. Factor Bioscience was founded in 2011 and is based in Cambridge, Massachusetts.


DEAL STATS #
Overall 2 of 2
Sector: Life Science M&A 2 of 2
Type: Divestiture M&A Deals 2 of 2
State: Massachusetts M&A 2 of 2
Country: United States M&A 2 of 2
Year: 2025 M&A 1 of 1
PREVIOUS DEAL
DATE TARGET DEAL TYPE VALUE
2021-06-14 Novellus Therapeutics

Cambridge, Massachusetts, United States

Novellus Therapeutics is a company developing next-generation engineered mesenchymal stem cell therapies using patented mRNA cell reprogramming and gene editing technologies. Novellus Therapeutics was founded in 2015 and is based in Cambridge, Massachusetts.

Sell $125M