Add-on Acquisition • Life Science

PainReform Acquires LayerBio

On August 12, 2025, PainReform acquired life science company LayerBio

Acquisition Context
  • This is PainReform’s 1st transaction in the Life Science sector.
  • This is PainReform’s 1st transaction in the United States.
  • This is PainReform’s 1st transaction in Massachusetts.

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M&A Deal Summary

Date August 12, 2025
Target LayerBio
Sector Life Science
Buyer(s) PainReform
Deal Type Add-on Acquisition

Target Company

LayerBio

Lexington, Massachusetts, United States
LayerBio is a biotechnology company advancing sustained-release drug delivery technologies in ophthalmology. The company's lead product candidate OcuRing, is a patent-protected, sustained-release intraocular ring designed to deliver Ketoralac, an anti-inflammatory and analgesic drug, to be introduced intra-surgically during cataract procedures. It is a bioerodible implant that offers a transformative alternative to the current standard of care, which commonly relies on frequent topical eye drops, including corticosteroids and NSAIDs. LayerBio is based in Lexington, Massachusetts.
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Buyer Overview 1

Buyer

PainReform

Tel Aviv, Israel

Category Company
Founded 2007
Sector Life Science
Employees2
Revenue 10M USD (2023)
DESCRIPTION

PainReform is a specialty pharmaceutical company that engages in the development of products for the treatment of pain in Israel. The company develops PRF-110, a product based on local anesthetic ropivacaine, which completed Phase II clinical study in hernia repair. PainReform was founded in 2007 and is based in Tel Aviv, Israel.


Deal Context for Buyer #
Overall 2 of 2
Sector: Life Science 1 of 1
Type: Add-on Acquisition 1 of 1
State: Massachusetts 1 of 1
Country: United States 1 of 1
Year: 2025 2 of 2
PREVIOUS DEAL
DATE TARGET DEAL TYPE VALUE
2025-02-18 DeepSolar

Ramat Gan, Israel

DeepSolar is an AI-powered analytics company that optimizes the efficiency and profitability of solar energy assets. DeepSolar leverages proprietary software and AI-driven automation tools, providing a significant competitive advantage in solar energy management.

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