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  6. PainReform Acquires LayerBio

M&A Deal Summary

PainReform Acquires LayerBio

On August 12, 2025, PainReform acquired life science company LayerBio

Acquisition Highlights
  • This is PainReform’s 1st transaction in the Life Science sector.
  • This is PainReform’s 1st transaction in the United States.
  • This is PainReform’s 1st transaction in Massachusetts.

M&A Deal Summary
Date 2025-08-12
Target LayerBio
Sector Life Science
Buyer(s) PainReform
Deal Type Add-on Acquisition

Target

LayerBio

Lexington, Massachusetts, United States
LayerBio is a biotechnology company advancing sustained-release drug delivery technologies in ophthalmology. The company's lead product candidate OcuRing, is a patent-protected, sustained-release intraocular ring designed to deliver Ketoralac, an anti-inflammatory and analgesic drug, to be introduced intra-surgically during cataract procedures. It is a bioerodible implant that offers a transformative alternative to the current standard of care, which commonly relies on frequent topical eye drops, including corticosteroids and NSAIDs. LayerBio is based in Lexington, Massachusetts.

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Buyer(S) 1

Buyer

PainReform

Tel Aviv, Israel
Category Company
Founded 2007
Sector Life Science
Employees2
Revenue 10M USD (2023)
DESCRIPTION

PainReform is a specialty pharmaceutical company that engages in the development of products for the treatment of pain in Israel. The company develops PRF-110, a product based on local anesthetic ropivacaine, which completed Phase II clinical study in hernia repair. PainReform was founded in 2007 and is based in Tel Aviv, Israel.

DEAL STATS #
Overall 2 of 2
Sector: Life Science M&A 1 of 1
Type: Add-on Acquisition M&A Deals 1 of 1
State: Massachusetts M&A 1 of 1
Country: United States M&A 1 of 1
Year: 2025 M&A 2 of 2
PREVIOUS DEAL
DATE TARGET DEAL TYPE VALUE
2025-02-18 DeepSolar

Ramat Gan, Israel

DeepSolar is an AI-powered analytics company that optimizes the efficiency and profitability of solar energy assets. DeepSolar leverages proprietary software and AI-driven automation tools, providing a significant competitive advantage in solar energy management.

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